Pharmacokinetics and Pharmacodynamics

Understanding pharmacokinetics (PK) and pharmacodynamics (PD) is essential for designing safe and effective drug therapies. PK describes how the body absorbs, distributes, metabolizes, and excretes a drug, while PD focuses on the drug’s biological effects. Modeling and simulation tools help predict human response, optimize dosing, and support regulatory submissions. Integrating PK/PD data with formulation and delivery system design ensures improved efficacy, reduced toxicity, and successful translation from bench to bedside. Personalized medicine increasingly relies on PK/PD insights for tailored therapies.

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